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Israeli-Italian Collaboration Targets Life-Threatening Condition in Preemies

Israel’s Elgan Pharma and Italy’s Chiesi Farmaceutici have begun dosing infants in a Phase 3 clinical trial of ELGN-2112, a potential ...

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Jerusalem, 5 June, 2025 (TPS-IL) — Israel’s Elgan Pharma and Italy’s Chiesi Farmaceutici have begun dosing infants in a Phase 3 clinical trial of ELGN-2112, a potential breakthrough treatment for intestinal malabsorption in preterm babies. The global FIT-PIV study will enroll 420 infants across 50 sites, aiming to improve gastrointestinal function and reduce complications linked to intravenous feeding.

ELGN-2112, an enteral insulin formulation, has shown promise in accelerating nutritional development in earlier trials. The Israeli-Italian collaboration marks a significant step toward addressing a serious and often life-threatening condition affecting premature infants worldwide.

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Thursday, 5 March 2026 Updated continuously